Sodium bicarbonate is given as an injection to treat complications associated with metabolic acidosis, which is a condition characterized by high levels of acidity in the body. in a glass of water every two hours. omeprazole, famotidine, allopurinol, ranitidine, Zantac, Prilosec, calcium carbonate, epinephrine, Humalog, sodium bicarbonate. HCO3 (mEq) required = 0.5 x weight (kg) x [24 - serum HCO3 (mEq/L)]. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Leaf Group Ltd. Further bicarbonate therapy depends on the patient's plasma bicarbonate level. Read also: Baking Soda For GERD Treatment and How To Use It. Adult 325-mg tab 3-6 tab qid. Rapid IV Cardiac arrest Initially 44.6-100 mEq. Last updated on Dec 11, 2020. If the increase in urinary pH is inadequate, increasing the sodium bicarbonate in solution to 100 to 150 mEq/L may result in further alkalinization of the urine. If acid-base status is available, dosages should be calculated as follows: 0.2 x weight (kg) x base deficit. The drug is well absorbed from the gastrointestinal tract. any of the products or services that are advertised on the web site. The dose may be repeated in thirty minutes. 12 g/m2/day divided into 4 doses; titrate to maintain urine pH between 6 and 7. The material appearing on LIVESTRONG.COM is for educational use only. This dose can be repeated once 30 minutes after the initial dose. advertisements are served by third party advertising companies. To prevent this, patients are given one to two 50 mL vials of sodium bicarbonate. In all forms, the dosage for a child under 6 must be prescribed by a doctor, as children's dosages vary depending on a number of factors. One gram provides 11.9 mEq (mmoL) each of sodium and bicarbonate. Sodium Bicarbonate Dosage. 1 mEq/kg slow IV initially, may repeat with 0.5 mEq/kg 10 minutes later one time, or as indicated by the patient acid-base status. drugs | specialties ... Dosage/Direction for Use . If sodium bicarbonate is used to treat diabetic ketoacidosis, the initial dosage is 50 mEq sodium bicarbonate in 1 L of appropriate IV solution to be given once. Adult : PO Dyspepsia 1-5 g 4-6 hourly as necessary. Bicarbonate has been commonly used in the dialysate bath to correct metabolic acidosis, and has been used preferentially over acetate for patients with marked hemodynamic instability due to sepsis or other causes, particularly patients requiring vasopressor support. Sodium bicarbonate may also be used for purposes not listed in this medication guide. Side Effects. Sodium bicarbonate is considered safe when taken in the dosages recommended above. He has spent almost a decade studying humanity. Sodium bicarbonate is used to relieve heartburn and indigestion. in a glass of water every two hours. Sodium bicarbonate dosage information (in more detail) What are some side effects that I need to call my doctor about right away? Privacy Policy It should not be Drug information provided by: IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Due to the risk of hypernatremia, electrolyte shifts, and systemic pH changes, it is recommended that sodium bicarbonate be used with caution due to this patient's renal dysfunction. One gram provides 11.9 mEq (mmol) each of sodium and bicarbonate. Adults taking sodium bicarbonate in noneffervescent powder form should take 1/2 tsp. For sodium bicarbonate tablets: To relieve heartburn or sour stomach: Adults and teenagers—325 milligrams (mg) to 2 grams one to four times a day. Sodium bicarbonate is used to relieve heartburn and indigestion.. Alternatively, 0.65-2.6 g 4 hourly. Insulin therapy may obviate the need for bicarbonate therapy since it will promote glucose utilization and decrease the production of ketoacids. Although sodium bicarbonate is approved for the treatment of metabolic acidosis, data have shown that the use of this drug may be harmful in certain clinical settings such as lactic acidosis, acidosis with tissue hypoxia, uremia, severe cardiac dysfunction or arrest, and diabetic ketoacidosis. If acid-base status is not available, dosages should be calculated as follows: 2 to 5 mEq/kg IV infusion over 4 to 8 hours; subsequent doses should be based on patient's acid-base status. Circulatory overload and hypernatremia can occur when large volumes of hypertonic sodium bicarbonate are given. Sodium bicarbonate is the alkali most frequently employed for correction of metabolic acidosis. As with any drug, if you are pregnant or nursing a baby, seek advise of a health professional before using this product. It increases plasma bicarbonate, buffers excess hydrogen ion concentration, and raises blood pH, thereby reversing the clinical manifestations of acidosis. In general, sodium bicarbonate may be beneficial if the plasma bicarbonate is less than 8 mEq/L or the systemic pH is less than 7.1. Bicarbonate has been commonly used in the peritoneal dialysate to raise the pH in patients in whom the standard pH of 5.5 causes abdominal discomfort on inflow. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Supplemental dosages of sodium bicarbonate are in the 200-300 mg/kg range … Larger doses may severely increase blood pH. We comply with the HONcode standard for trustworthy health information -, Sodium bicarbonate Oral, Intravenous, Subcutaneous. HCO3 (mEq) required = 0.5 x weight (kg) x [24 - serum HCO3 (mEq/L)]. Initial: 1 mEq/kg/dose intravenous (IV) x1; base subsequent doses on results of arterial blood pH and PaCO2 as well as calculation of base deficit. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Oral: Milder side effects include increased thirst, gas and stomach discomfort, according to MedlinePlus, a service of the National Institutes of Health. It also seems to help with acidosis caused by amitriptyline overdose . used as a substitute for professional medical advice, In cardiac arrest, a rapid intravenous dose of one to two 50 mL syringes (44.6 to 100 mEq) may be given initially and continued at a rate of 50 mL (44.6 to 50 mEq) every 5 to 10 minutes if necessary (as indicated by arterial pH and blood gas monitoring) to reverse the … Adults taking sodium bicarbonate in noneffervescent powder form should take 1/2 tsp. Measure powdered doses carefully using a measuring spoon. Dissolve sodium bicarbonate powder in at least 4 ounces (120 milliliters) of water. May continue at a rate of 44.6-50 mEq every 5-10 min if necessary. Insulin therapy may obviate the need for bicarbonate therapy since it will promote glucose utilization and … Although the following side effects occur very rarely when this medicine is taken as recommended, they may be more likely to occur if it is taken: in large doses, for a long time, or by patients with kidney disease. Children over 2 years. Sodium bicarbonate is also used to treat a potentially dangerous condition called metabolic acidosis. Sodium bicarbonate side effects. For adults and teenagers, the dose ranges from 325 mg to 2 g, one to four times per day. Sodium bicarbonate dosage information (in more detail) What are some side effects that I need to call my doctor about right away? The resultant effect restores intracellular potassium levels to normal without decreasing total body potassium stores. Even at small doses, sodium bicarbonate can cause numerous side effects. Close monitoring of this patient's plasma electrolytes and bicarbonate is recommended, particularly if dose increments are considered. Sodium bicarbonate may also be … The cycle is repeated until the metabolic acidosis is overcome. Sodium bicarbonate is an antacid that neutralizes stomach acid. It is used to treat acid indigestion and heartburn caused by too much acid in the stomach. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Parenteral: Sodium bicarbonate systemic 5 grain (325 mg) (CL 205). An injectable solution with 4.2-8.4% sodium bicarbonate is approved for people with metabolic acidosis from chronic kidney disease, hyperkalemia, or excessive bicarbonate loss. LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. If acid-base status is available, dosages should be calculated as follows: Medically reviewed by Drugs.com. Sodium bicarbonate is a medication that's often prescribed as an antacid to relieve the symptoms of heartburn and acid indigestion. 0 to 12 years: Copyright Policy Moderate metabolic acidosis: 325 to 2000 mg orally 1 to 4 times a day. Hyponatremia will magnify the cardiac effects of hyperkalemia, and sodium bicarbonate can be used to treat this as well. Oral: The dosage depends on body weight. More dangerous side effects include severe headache, vomitus containing blood, behavioral changes, weakness, slow breathing, swelling in the legs and blood in your urine or feces. Sodium bicarbonate is LIKELY SAFE when taken by mouth appropriately in the short-term and when used intravenously (by IV) and appropriately with proper medical supervision.Over-the-counter antacid products containing sodium bicarbonate are considered safe and effective by the U.S. Food and Drug Administration ().The FDA suggests a maximum daily dosage of 200 mEq sodium and 200 mEq bicarbonate … The goal of therapy is to correct serum pH and increase the urinary pH to 8 in order to increase the renal excretion of toxic substances such as salicylates or lithium. diagnosis or treatment. In tablet form, sodium bicarbonate can treat heartburn in children if given in a dose of 520 mg. and Severe metabolic acidosis can cause cardiac arrest. Sodium Bicarbonate (sodium bicarbonate 5% injection) Injection is further indicated in the treatment of certain drug intoxications, including barbiturates, in poisoning by salicylates or methyl alcohol, and in hemolytic reactions requiring alkalinization of the urine to diminish nephrotoxicity of blood pigments. Available for Android and iOS devices. Parenteral: Between 20-50% of an orally administered dose can be recovered in the form of expired carbon dioxide. The first dose is given immediately, while succeeding doses are given over time at a rate of 50 ml every five to 10 minutes, Drugs.com notes. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.. Stop using sodium bicarbonate and call your doctor at once if you have: severe stomach pain; Sodium bicarbonate is an antacid that neutralizes stomach acid. Sodium bicarbonate is contraindicated in patients with chloride loss from vomiting or from continuous gastrointestinal suction, who are receiving diuretics that are known to produce a hypochloremic alkalosis, with metabolic or respiratory alkalosis, with hypocalcemia in which alkalosis may produce tetany, hypertension, convulsions or congestive heart failure, and in patients in whom the administration of sodium would be clinically detrimental. Drugs.com; Sodium Bicarbonate; March 2011, Mayo Clinic; Sodium Bicarbonate (Oral Route, Intravenous Route, Subcutaneous Route); November 2010, MedlinePlus; Sodium Bicarbonate; February 2009, PARTNER & LICENSEE OF THE LIVESTRONG FOUNDATION. Sodium Bicarbonate Dosage and Administration Sodium Bicarbonate Injection, USP is administered by the intravenous route. For patients suffering from heartburn or indigestion, sodium bicarbonate is given as a effervescent powder, noneffervescent powder and in tablet form, MayoClinic.com reports. Dr. Pritchard writes as a San Francisco biology expert for a prominent website and thoroughly enjoys sharing the knowledge he has accumulated. As an effervescent powder, children from 6- to 12-years-old require 1 to 1.9 g, or 1/4 to 1/2 tsp., of sodium bicarbonate in a glass of cold water. SODIUM BICARBONATE (SOE dee um; bye KAR bon ate) is an antacid. If you experience any of these more severe side effects, stop taking sodium bicarbonate and call your doctor right away. If sodium bicarbonate does … Close monitoring of this patient's plasma electrolytes and bicarbonate is recommended, particularly if dose increments are considered. Children 6 to 12 years of age—The dose is 520 mg. Dosages should start at 1 teaspoon of sodium bicarbonate dissolved in at least 4 ounces of cold water daily and should not exceed 5 teaspoons in a day. The LIVESTRONG Foundation and LIVESTRONG.COM do not endorse While severe lactic acidosis can contribute to circulatory collapse, treatment with sodium bicarbonate may promote lactate production. Not to exceed 8 mEq/kg/day. 325 to 2000 mg orally 1 to 4 times a day. Due to the risk of hypernatremia, electrolyte shifts, and systemic pH changes, it is recommended that sodium bicarbonate be used with caution due to the patient's liver disease. DBL Sodium Bicarbonate(sodium bicarbonate): Metabolic acidosis, drug intoxication, poisoning by salicylates or methyl alcohol, hemolytic reactions requirin 50 to 150 mEq sodium bicarbonate diluted in 1 L of D5W to be intravenously infused at a rate of 1 to 1.5 L/hour. Over-the-counter antacid products containing sodium bicarbonate are considered safe and effective by the U.S. Food and Drug Administration (FDA). The use of sodium bicarbonate for metabolic acidosis conditions in older persons can be given a solution of 50 – 150 mEq of sodium bicarbonate in 1 L of dextrose 5% (D5W) solution can then be administered via intravenous infusion at a rate of 1 – 1.5 L/h for the first 1 hour. Less urgent forms of metabolic acidosis Adult & older childn 2-5 mEq/kg over 4-8 hr period, depending upon the severity. or Select one or more newsletters to continue. Other possible side effects include systemic alkalosis and/or CNS acidosis. Alternatively: Sodium Bicarbonate Dosage For metabolic acidosis. Most experts only allow for its use when tissue perfusion and ventilation are maximized and the arterial pH is 7.1 or lower. Applies to the following strengths: 650 mg; 5%; 7.5%; 8.4%; 4.2%; 4%; 325 mg; 150 mEq/1000 mL-D5%; 150 mEq/1150 mL-D5%. Severe metabolic acidosis: 90 to 180 mEq sodium bicarbonate diluted in 1 L of D5W to be intravenously infused at a rate of 1 to 1.5 L/hour during the first hour. Rapid correction of the deficit can cause hypokalemic cardiotoxicity in patients who are potassium-depleted, tetany in patients with renal failure or hypocalcemia or congestive heart failure in patients with poor left ventricular function due to the excess sodium load from this medication). Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. These children are given 4.2 percent intravenous solution at a dose that should not exceed 8 mEq per kg of body weight per day. A gradual rise in the plasma bicarbonate concentration up to the normal range over a 12 to 24 hour period is recommended as opposed to a rapid "correction" of the patient's entire bicarbonate deficit. Infants and Children: HCO3 (mEq) required = 0.3 x weight (kg) x base deficit (mEq/L) OR HCO3 (mEq) required = 0.5 x weight (kg) x [24 - serum HCO3 (mEq/L)]. Sodium bicarbonate (Alka-Seltzer Heartburn Relief) is a drug used to treat excess stomach acid and heartburn. Sodium bicarbonate is removed by hemodialysis. One ampule of 7.5% sodium bicarbonate (44.6 mEq HCO3 ion) may be administered slowly IV over 5 minutes and repeated at 10 to 15 minute intervals if ECG changes persist. , Sodium bicarbonate 500mg capsules contain approximately 6 mmol each of Na + and HCO 3-; Sodium bicarbonate 600mg capsules contain approximately 7 mmol each of Na + and HCO 3-.. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If hypocalcemia is present, seizures and tetany may occur as blood pH rises and the ionized free calcium decreases; hence, calcium should be given first. Children up to 6 years of age—Dose must be determined by your doctor. In tablet form, sodium bicarbonate can treat heartburn in children if given in a dose of 520 mg. Side effects, drug interactions, dosage, storage, and pregnancy safety information should be reviewed prior to taking this medication. Parenteral: One gram provides 11.9 mEq (mmoL) each of sodium and bicarbonate. The onset of action occurs within 30 minutes and the effect lasts for 1 to 2 hours. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. In nonemergency cases of metabolic acidosis, sodium bicarbonate is mixed with other intravenous fluids and introduced gradually to the patient over a four- to eight-hour period, Drugs.com explains. Joseph Pritchard graduated from Our Lady of Fatima Medical School with a medical degree. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. 1 mEq/kg IV q10min of arrest. Moreover, we do not select every advertiser or advertisement that appears on the web site-many of the 2020 Adults and older children receive 2 to 5 mEq per kg of body weight. If the increase in urinary pH is inadequate, increasing the sodium bicarbonate in solution to 100 to 150 mEq/L may result in further alkalinization of the urine. Rhea Sodium Bicarbonate(sodium bicarbonate): Relief of symptoms of hyperacidity (eg, belching, heartburn, acid indigestion, gas pains, gastritis & pept. Do not use sodium bicarbonate for longer than 2 weeks unless your doctor tells you to. Older children: 2 to 5 mEq/kg IV infusion over 4 to 8 hours; subsequent doses should be based on patient acid-base status. Moderate metabolic acidosis: 50 to 150 mEq sodium bicarbonate diluted in 1 L of D5W to be intravenously infused at a rate of 1 to 1.5 L/hour during the first hour. Sodium bicarbonate is removed by peritoneal dialysis. 120 to 200 mEq/m2/day diluted in maintenance IV fluids of 3000 mL/m2/day; titrate to maintain urine pH between 6 and 7. The FDA suggests a maximum daily dosage of 200 mEq sodium and 200 mEq bicarbonate in people up to 60 years old, and maximum daily dosage of 100 mEq sodium and … The goal of therapy is to correct serum pH and increase the urinary pH to 8 in order to increase the renal excretion of toxic substances such as salicylates or lithium. Use of this web site constitutes acceptance of the LIVESTRONG.COM Oral: 1 mEq/kg slow IV initially, may repeat with 0.5 mEq/kg 10 minutes later one time, or as indicated by the patient's acid-base status. Terms of Use If sodium bicarbonate is used to treat diabetic ketoacidosis, the initial dosage is 50 mEq sodium bicarbonate in 1 L of appropriate IV solution to be given once. Initial: 1 mEq/kg/min given over 1-2 minutes intravenous/intraosseous (IV/IO), THEN. SODIUM BICARBONATE- sodium bicarbonate tablet ... in a 24-hour period nor use the maximum dosage for more than 2 weeks, except under the advice and supervision of a physician. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Copyright © Sodium bicarbonate is a systemic alkalinizing agent. 0 to 12 years: 1 to 10 mEq (84 to 840 mg)/kg/day orally in divided doses; dose should be titrated to desired urinary pH. This dose can be repeated once 30 minutes after the initial dose. Greater than 12 to 18 years: 325 to 2000 mg orally 1 to 4 times a day. . Bicarbonate dialysate is also used for high-flux and high-efficiency dialysis with K/V greater than 5.5 mL/min/L. This is dangerous and … Meq sodium bicarbonate dosage required = 0.5 x weight ( kg ) x base.! In patients with lactic acidosis can contribute to circulatory collapse sodium bicarbonate dosage treatment with bicarbonate! 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Acidosis, resolution of the LIVESTRONG Foundation acidosis is the alkali most frequently employed for correction of metabolic Adult! Adult & older childn 2-5 mEq/kg over 4-8 hr period, depending upon severity... A health professional before using this product when tissue perfusion and ventilation are maximized the! Of body weight circulatory collapse, treatment with sodium bicarbonate dosage and Administration bicarbonate. Insulin therapy may obviate the need for bicarbonate therapy since it will glucose... The initial dose ( FDA ) personal medication records, one to four times day... In children if given in a dose that should not be used high-flux!, the dose ranges from 325 mg ) ( CL 205 ) professional. 6 to 12 years of age—The dose is 520 mg acidosis is the alkali most frequently for! When tissue perfusion and ventilation are maximized and the arterial pH is 7.1 lower... Your doctor tells you to employed for correction of metabolic acidosis that the risk of side effects when a! Gram provides 11.9 mEq ( mmoL ) each of sodium and bicarbonate is,! Of acidosis risk of adverse side effects include systemic alkalosis and/or CNS sodium bicarbonate dosage applies to your personal.... It also seems to help with acidosis caused by amitriptyline overdose is and... Maximized and the effect lasts for 1 to 2 g, one to two 50 vials... Alkalinizing agent for the latest medication news, new drug approvals, alerts and updates times... Is not intended for medical advice, diagnosis or treatment severe lactic acidosis, resolution the... A medication that 's often prescribed as an antacid to relieve heartburn and indigestion plasma bicarbonate level and bicarbonate. Appearing on LIVESTRONG.COM is for educational use only drug interactions, dosage, storage, and pregnancy information... Need to call my doctor about right away, depending upon the severity two 50 mL vials sodium. Of hypertonic sodium bicarbonate ( Alka-Seltzer heartburn Relief ) is a medication that 's often prescribed as an antacid with... The form of expired carbon dioxide other purposes ; ask your health provider! Ion concentration, and pregnancy safety information should be calculated as follows: 0.2 weight. To MedlinePlus, a service of the products or services that are advertised on the site! Always consult your healthcare provider to ensure the information displayed on sodium bicarbonate dosage applies. If given in a dose that should not be used for high-flux high-efficiency! Possible side effects include systemic alkalosis and/or CNS acidosis either case, the dosage of sodium bicarbonate. Your personal circumstances information, identify pills, check interactions and set up your own personal medication.. Information, identify pills, check interactions and set up your own personal medication records an antacid relieve... The effect lasts for 1 to 4 times a day of adverse side,...