Ten years after Izzie left screens, her character returned to help wrap up Karev's storylines in Season 16. The fate of Alex Karev was revealed during the March 5 episode of ‘Grey’s Anatomy.’ The show bid farewell to the beloved character and Izzie Stevens was brought back into the pict… Izzie left Seattle midway through Season 6 and gets referenced again in the following seasons, but ended up really stealing the show during Season 16, Episode 16.

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