Variations in infant CYP2B6 genotype associated with the need for pharmacological treatment for neonatal abstinence syndrome in infants of methadone-maintained opioid-dependent mothers. Description Maternal drug use and intrauterine exposure of the fetus during pregnancy can lead to drug withdrawal in the infant after delivery. A multi-faceted approach will be the most effective for addressing NAS and should include prevention strategies that directly impact the cycle of addiction, spanning the social determinants of health, including poverty and lack of access to healthcare and education. Neonatal abstinence syndrome (NAS) was first described in the 1970s, identified among neonates whose mothers most commonly used heroin or were on methadone maintenance. A new CDC article looked at laws enacted in six states that make health departments or hospitals report all babies born with NAS for public health monitoring. Infants who are diagnosed with drug withdrawal after birth who are treated with medication as outpatients at home are treated three times longer than infants treated solely as inpatients, according to a new Vanderbilt study.
Neonatal abstinence syndrome (NAS) is a drug withdrawal syndrome that occurs shortly after birth, and can occur when an infant is exposed to an opioid during the pregnancy. Karen G, Cairns J, Chitayat D, Gaedick A, Leader SJ. Clinical Policy: Neonatal Abstinence Syndrome Guidelines Reference Number: CP.MP.86 Effective Date: 10/13 Last Review Date: 10/17 Revision Log See Important Reminder at the end of this policy for important regulatory and legal information. Am J Perinatol 2017;34:918-21; https://www.bapm.org/resources/framework-neonatal-transitional-care. Neonatal abstinence syndrome (NAS) is a withdrawal syndrome that can occur in newborns exposed to certain substances, including opioids, during pregnancy. Neonatal Abstinence Syndrome. One of the many unfortunate results of the epidemic is a dramatic upsurge in cases of opioid dependency by expectant women that result in children born with Neonatal Abstinence Syndrome (NAS). 1 NAS refe The United States is currently in the midst of an opioid epidemic that has hit states in the southern New England regions particularly hard — with Massachusetts as one primary example. The neonatal abstinence syndrome refers to a postnatal opioid withdrawal syndrome that can occur in 55 to 94% of newborns whose mothers were addicted to or treated with opioids while pregnant.
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